Murrough O'Brien

Murrough O'Brien may refer to:

• Murrough O'Brien, 1st Earl of Thomond (d. 1551)
• Murrough O'Brien, 4th Baron Inchiquin (d. 1597)
• Murrough O'Brien, 1st Earl of Inchiquin (c.1618 - 1674)
• Murrough O'Brien, 1st Marquess of Thomond (1726-1808)