Missile lock-on is when the guidance system for a missile (or its associated launch vehicle) can accurately track a target, and a fire-control system can calculate the required flightpath for the missile to intercept the target. Missile lock-on is typically indicated to the pilot or missile operator via an audible tone, a head-up display or a helmet-mounted display.
Read more about Missile Lock-on: Detection By The Target, See Also
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—George Eliot [Mary Ann (or Marian)