Metastasis - Management

Management

Treatment and survival is determined, to a great extent, by whether or not a cancer remains localized or spreads to other locations in the body. If the cancer metastasizes to other tissues or organs, it usually dramatically decreases a patient's likelihood of survival (i.e. the "prognosis"). However, there are some cancers - such as some forms of leukemia, a cancer of the blood, or malignancies in the brain - that can kill without spreading at all.

Once a cancer has metastasized, it may still be treated with radiosurgery, chemotherapy, radiation therapy, biological therapy, hormone therapy, surgery, or a combination of these interventions ("multimodal therapy"). The choice of treatment depends on a large number of factors, including the type of primary cancer, the size and location of the metastases, the patient's age and general health, and the types of treatments used previously, among others. In patients diagnosed with CUP, it is often still possible to treat the disease even when the primary tumor cannot be located.

The treatment options currently available are rarely able to cure metastatic cancer, though some tumors, such as testicular cancer and thyroid cancer, are usually still curable.

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