Comics
- Mercury (Marvel Comics), a character who can turn herself into a mercurial substance
- Mercury (Amalgam Comics), a combination of the characters Impulse and Quicksilver
- Makkari (comics), a Marvel Comics character formerly known as Mercury
- Mercury, a member of the Metal Men, a DC comics team
- Mercury, a member of Cerebro's X-Men
- Sailor Mercury, a character from Sailor Moon
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