Other
- Andrew W. Mellon Foundation, private foundation with five core areas of interest, endowed with wealth accumulated by Andrew W. Mellon
- Andrew W. Mellon Auditorium, a U.S. government-owned auditorium in Washington, D.C.'s Federal Triangle
- Carnegie Mellon University, leading university in Pittsburgh
- Mellon Institute, research institute founded by the Mellon family, merged to become Carnegie Mellon University
- Mellon College of Science, science college at Carnegie Mellon University
- Mellon Financial, a wholly owned subsidiary of The Bank of New York Mellon Corporation
- Mellon Arena, home of the NHL Pittsburgh Penguins
- Mellon Square, Square located in Pittsburgh
- Mellon Collie and the Infinite Sadness, Smashing Pumpkin's 1995 2-disc album
- Mellon (meaning "friend") is the password to enter Moria in the novel The Lord of the Rings
- Mellon (newspaper), a Greek socialist newspaper
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