MEF2C
| Gene Ontology | |
|---|---|
| Molecular function | • RNA polymerase II regulatory region sequence-specific DNA binding • sequence-specific DNA binding RNA polymerase II transcription factor activity • RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity • RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription • DNA binding • AT DNA binding • sequence-specific DNA binding transcription factor activity • protein binding • activating transcription factor binding • miRNA binding • transcription regulatory region DNA binding • protein heterodimerization activity |
| Cellular component | • nucleus • nucleoplasm • nucleolus • cytoplasm • nuclear speck • intracellular membrane-bounded organelle • protein complex |
| Biological process | • negative regulation of transcription from RNA polymerase II promoter • MAPK cascade • blood vessel development • osteoblast differentiation • B cell homeostasis • heart looping • endochondral ossification • blood vessel remodeling • chondrocyte differentiation • toll-like receptor signaling pathway • germinal center formation • regulation of germinal center formation • MyD88-dependent toll-like receptor signaling pathway • MyD88-independent toll-like receptor signaling pathway • primary heart field specification • secondary heart field specification • outflow tract morphogenesis • sinoatrial valve morphogenesis • cardiac ventricle formation • transcription from RNA polymerase II promoter • apoptotic process • humoral immune response • nervous system development • heart development • muscle organ development • skeletal muscle tissue development • muscle cell fate determination • learning or memory • Toll signaling pathway • response to virus • positive regulation of gene expression • negative regulation of gene expression • positive regulation of alkaline phosphatase activity • neural crest cell differentiation • myotube differentiation • neuron differentiation • platelet formation • negative regulation of ossification • melanocyte differentiation • positive regulation of bone mineralization • positive regulation of B cell proliferation • toll-like receptor 1 signaling pathway • toll-like receptor 2 signaling pathway • toll-like receptor 3 signaling pathway • toll-like receptor 4 signaling pathway • TRIF-dependent toll-like receptor signaling pathway • cellular response to drug • cellular response to trichostatin A • B cell proliferation • muscle cell differentiation • negative regulation of apoptotic process • negative regulation of neuron apoptotic process • innate immune response • regulation of megakaryocyte differentiation • positive regulation of myoblast differentiation • positive regulation of neuron differentiation • positive regulation of osteoblast differentiation • positive regulation of transcription, DNA-dependent • positive regulation of transcription from RNA polymerase II promoter • nerve growth factor receptor signaling pathway • positive regulation of skeletal muscle tissue development • neuron development • B cell receptor signaling pathway • smooth muscle cell differentiation • positive regulation of muscle cell differentiation • stress-activated MAPK cascade • ventricular cardiac muscle cell differentiation • regulation of synaptic activity • positive regulation of cardiac muscle cell proliferation • renal tubule morphogenesis • cellular response to lipopolysaccharide • cellular response to calcium ion • cellular response to parathyroid hormone stimulus • cellular response to fluid shear stress • cellular response to transforming growth factor beta stimulus • glomerulus morphogenesis • nephron tubule epithelial cell differentiation • positive regulation of protein homodimerization activity • positive regulation of macrophage apoptotic process • positive regulation of cardiac muscle cell differentiation • positive regulation of behavioral fear response • epithelial cell proliferation involved in renal tubule morphogenesis • positive regulation of skeletal muscle cell differentiation |
| Sources: Amigo / QuickGO | |
88.01 – 88.2 Mb
83.5 – 83.67 Mb
Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene. MEF2C is a transcription factor in the Mef2 family.
Read more about MEF2C: Genomics, Interactions, Biological Significance