Issue
| Name | Birth | Death | Notes |
|---|---|---|---|
| Louis XIII, King of France | 27 September 1601 | 14 May 1643 | Married Anne of Austria (1601–1666) in 1615. Had issue. |
| Elisabeth, Queen of Spain | 22 November 1602 | 6 October 1644 | Married Philip IV, King of Spain (1605–1665) in 1615. Had issue. |
| Christine, Duchess of Savoy | 12 February 1606 | 27 December 1663 | Married Victor Amadeus I, Duke of Savoy (1587–1637) in 1619. Had issue. |
| Nicholas Henri, Duke of Orléans | 16 April 1607 | 17 November 1611 | Died young. |
| Gaston, Duke of Orléans | 25 April 1608 | 2 February 1660 | Married (1) Marie de Bourbon (1605–1627) in 1626. Had issue. Married (2) Marguerite of Lorraine (1615–1672) in 1632. Had issue. |
| Henrietta Maria, Queen of England | 25 November 1609 | 10 September 1669 | Married Charles I, King of England (1600–1649) in 1625. Had issue. |
The current second in line to the throne of the United Kingdom, Prince William, Duke of Cambridge, is descended from Marie through his mother, Diana, Princess of Wales's, descent from four illegitimate children of King Charles II of England and an illegitimate daughter of King James II of England. Both Charles II and James II were grandsons of Marie de Medici by her daughter Henrietta Maria. Through the marriage of her granddaughter Princess Henrietta Anne of England to her other grandson Phillipe Duc d'Orleans, Marie de Medici is the ancestress of most of the crowned and deposed royalty in Europe today. Princess Michael of Kent, born Baroness Marie Christine, is also a descendant by Marie's daughter, Christine. See also Descendants of Marie de' Medici which maps how the Medici became part of the European Royal families.
Read more about this topic: Marie De' Medici
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