Margaret Collins-O'Driscoll (née Collins; 1878 – 17 June 1945) was an Irish Cumann na nGaedheal politician. She was the sister of the Irish revolutionary leader Michael Collins. She was educated at Baggot Street Training College and was a schoolteacher and school principal before entering politics. She was first elected to Dáil Éireann as a Cumann na nGaedheal Teachta Dála (TD) for the Dublin North constituency at the 1923 general election. She was re-elected at every subsequent election until she lost her seat at the 1933 general election. Her great-granddaughter is the actress Dervla Kirwan.