Mapk14

MAPK14

Identifiers Symbols MAPK14; CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA External IDs OMIM: 600289 MGI: 1346865 HomoloGene: 31777 ChEMBL: 260 GeneCards: MAPK14 Gene EC number 2.7.11.24

Gene Ontology
Molecular function protein serine/threonine kinase activity
MAP kinase activity
MAP kinase kinase activity
protein binding
ATP binding
protein C-terminus binding
NFAT protein binding
Cellular component spindle pole
nucleus
nucleoplasm
cytoplasm
mitochondrion
cytosol
cytosolic part
Biological process DNA damage checkpoint
activation of MAPK activity
cell morphogenesis
angiogenesis
chondrocyte differentiation
toll-like receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
MyD88-independent toll-like receptor signaling pathway
glucose metabolic process
transcription, DNA-dependent
apoptotic process
cellular component movement
chemotaxis
response to stress
signal transduction
cell surface receptor signaling pathway
intracellular protein kinase cascade
Ras protein signal transduction
skeletal muscle tissue development
blood coagulation
Toll signaling pathway
response to glucose stimulus
gene expression
RNA metabolic process
mRNA metabolic process
peptidyl-serine phosphorylation
fatty acid oxidation
platelet activation
osteoclast differentiation
lipopolysaccharide-mediated signaling pathway
response to muramyl dipeptide
toll-like receptor 1 signaling pathway
toll-like receptor 2 signaling pathway
toll-like receptor 3 signaling pathway
toll-like receptor 4 signaling pathway
TRIF-dependent toll-like receptor signaling pathway
cellular response to vascular endothelial growth factor stimulus
muscle cell differentiation
signal transduction in response to DNA damage
positive regulation of blood vessel endothelial cell migration
innate immune response
positive regulation of erythrocyte differentiation
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
nerve growth factor receptor signaling pathway
regulation of sequence-specific DNA binding transcription factor activity
striated muscle cell differentiation
positive regulation of muscle cell differentiation
stress-activated MAPK cascade
3'-UTR-mediated mRNA stabilization
cellular response to ionizing radiation
stress-induced premature senescence
positive regulation of reactive oxygen species metabolic process
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 1432 26416 Ensembl ENSG00000112062 ENSMUSG00000053436 UniProt Q16539 P47811 RefSeq (mRNA) NM_001315 NM_001168508 RefSeq (protein) NP_001306 NP_001161980 Location (UCSC) Chr 6:
36 – 36.08 Mb Chr 17:
28.69 – 28.75 Mb PubMed search

Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene.

Read more about Mapk14.