MADS-box - Origin of Name

Origin of Name

The first MADS-box gene to be identified was ARG80 from budding yeast, Saccharomyces cerevisiae, but was at that time not recognized as a member of a large gene family. The MADS-box gene family got its name later as an acronym referring to the four founding members, ignoring ARG80:

  • MCM1 from the budding yeast, Saccharomyces cerevisiae,
  • AGAMOUS from the thale cress Arabidopsis thaliana,
  • DEFICIENS from the snapdragon Antirrhinum majus,
  • SRF from the human Homo sapiens.

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