Maco may refer to:
- Maco (film company), a German film company
- Maco (people), an indigenous people of South America
- Maco (toy company), which produced war-themed toys for children in the 1950s and 1960s
- Maco, Compostela Valley, a municipality in the Philippines
- Maco, North Carolina, an unincorporated community in Brunswick County, North Carolina, near Wilmington
- The Maco light, an allegedly paranormal event seen at the North Carolina community mentioned above
- MACO (Military Assault Command Operations), a fictional military unit seen in Star Trek: Enterprise
- MACO Door & Window Hardware (U.K.) Ltd, an Austrian manufacturer of window and door fittings