Compatibility
Snow Leopard breaks compatibility with several older versions of some applications, such as Parallels Desktop 3.0, versions of Aperture before 2.1.1, and versions of Keynote before 2.0.2, among other software. Apple has also published a list of applications with known compatibility issues with Snow Leopard.
Printer and scanner drivers used by previous versions of Mac OS X are not compatible with Snow Leopard and will be replaced during Snow Leopard installation. Since the initial release of Snow Leopard many manufacturers have provided compatible drivers that are available via Software Update. If a native driver is not available Snow Leopard also includes CUPS and Gutenprint open source drivers that may provide limited functionality.
10.6.0 introduced a bug that frequently prevented DNS queries from returning IPv6 addresses. This was resolved in 10.6.8.
Read more about this topic: Mac OS X Snow Leopard