LRP6
| Gene Ontology | |
|---|---|
| Molecular function | • low-density lipoprotein receptor activity • receptor binding • frizzled binding • protein binding • Wnt-protein binding • kinase inhibitor activity • toxin transporter activity • apolipoprotein binding • protein homodimerization activity • Wnt-activated receptor activity • coreceptor activity involved in Wnt receptor signaling pathway |
| Cellular component | • early endosome • endoplasmic reticulum • plasma membrane • caveola • cell surface • integral to membrane • cytoplasmic vesicle • neuronal cell body • receptor complex • synapse |
| Biological process | • gastrulation with mouth forming second • neural tube closure • negative regulation of protein phosphorylation • heart looping • positive regulation of mesenchymal cell proliferation • pericardium morphogenesis • negative regulation of protein kinase activity • synaptic transmission • embryonic pattern specification • anterior/posterior pattern specification • neural crest formation • neural crest cell differentiation • Wnt receptor signaling pathway • cerebellum morphogenesis • thalamus development • cerebral cortex cell migration • forebrain radial glial cell differentiation • Wnt receptor signaling pathway involved in forebrain neuroblast division • formation of radial glial scaffolds • cerebral cortex development • regulation of ossification • embryonic limb morphogenesis • midbrain development • midbrain-hindbrain boundary development • negative regulation of smooth muscle cell apoptotic process • embryonic forelimb morphogenesis • embryonic hindlimb morphogenesis • external genitalia morphogenesis • cell migration involved in gastrulation • odontogenesis of dentin-containing tooth • embryonic digit morphogenesis • positive regulation of apoptotic process • Wnt receptor signaling pathway involved in dorsal/ventral axis specification • canonical Wnt receptor signaling pathway involved in neural crest cell differentiation • canonical Wnt receptor signaling pathway involved in regulation of cell proliferation • regulation of fat cell differentiation • negative regulation of fat cell differentiation • positive regulation of ossification • positive regulation of bone resorption • positive regulation of cell cycle • positive regulation of transcription, DNA-dependent • positive regulation of transcription from RNA polymerase II promoter • bone remodeling • embryonic camera-type eye morphogenesis • negative regulation of epithelial cell proliferation • positive regulation of sequence-specific DNA binding transcription factor activity • response to folic acid • palate development • convergent extension • embryonic retina morphogenesis in camera-type eye • canonical Wnt receptor signaling pathway • regulation of cell development • face morphogenesis • bone morphogenesis • branching involved in mammary gland duct morphogenesis • trachea cartilage morphogenesis • mammary placode formation • canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development • canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation • cellular response to cholesterol • dopaminergic neuron differentiation • negative regulation of protein serine/threonine kinase activity • primitive streak formation • receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport • Wnt receptor signaling pathway involved in somitogenesis • axis elongation involved in somitogenesis • positive regulation of canonical Wnt receptor signaling pathway • positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification • negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis • negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis • negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis • negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis • negative regulation of planar cell polarity pathway involved in pericardium morphogenesis • negative regulation of planar cell polarity pathway involved in neural tube closure |
| Sources: Amigo / QuickGO | |
12.27 – 12.42 Mb
134.45 – 134.57 Mb
Low-density lipoprotein receptor-related protein 6 is a protein that in humans is encoded by the LRP6 gene.
Read more about LRP6: Interactions