Welterweight
| Name | Reign period | No. of successful defenses |
| Emile Griffith | December 8, 1962 – March 21, 1963 | 0 |
| Luis Manuel Rodríguez | March 21, 1963 – June 8, 1963 | 0 |
| Emile Griffith | June 8, 1963 – Apr 25,1966 (vacated) | 4 |
| Curtis Cokes def. Jean Josselin |
August 24, 1966 – April 18, 1969 | 4 |
| José Nápoles | April 18, 1969 – December 3, 1970 | 3 |
| Billy Backus | December 3, 1970 – June 4, 1971 | 0 |
| José Nápoles | June 4, 1971 – December 6, 1975 | 10 |
| John H. Stracey | December 6, 1975 – June 22, 1976 | 1 |
| Carlos Palomino | June 22, 1976 – January 14, 1979 | 7 |
| Wilfred Benítez | November 30, 1979 – January 14, 1979 | 1 |
| Sugar Ray Leonard | November 30, 1979 – June 20, 1980 | 1 |
| Roberto Durán | June 20, 1980 – November 25, 1980 | 0 |
| Sugar Ray Leonard | November 25, 1980 – November 9, 1982 (retired) | 3 |
| Milton McCrory def. Colin Jones |
August 13, 1983 – December 6, 1985 | 4 |
| Donald Curry | December 6, 1985 – September 27, 1986 | 0 |
| Lloyd Honeyghan | September 27, 1986 – October 28, 1987 | 3 |
| Jorge Vaca | October 28, 1987 – March 29, 1988 | 0 |
| Lloyd Honeyghan | March 29, 1988 – February 4, 1989 | 1 |
| Marlon Starling | February 4, 1989– August 19, 1990 | 1 |
| Maurice Blocker | August 19, 1990 – March 18, 1991 | 0 |
| Simon Brown | March 18, 1991 – November 29, 1991 | 0 |
| James McGirt | November 29, 1991 – March 6, 1993 | 2 |
| Pernell Whitaker | March 6, 1993 – April 12, 1997 | 8 |
| Oscar De La Hoya | April 12, 1997 – September 18, 1999 | 9 |
| Félix Trinidad | September 18, 1999 – March 3, 2000 (vacated) | 0 |
| Oscar De La Hoya | 3 March 2000 – 17 June 2000 | 0 |
| Shane Mosley | June 17, 2000 – January 26, 2002 | 3 |
| Vernon Forrest | January 26, 2002 – January 25, 2003 | 1 |
| Ricardo Mayorga | January 25, 2003 – December 13, 2003 | 1 |
| Cory Spinks | December 13, 2003 – February 5, 2005 | 2 |
| Zab Judah | February 5, 2005 – January 7, 2006 | 1 |
| Carlos Manuel Baldomir | January 7, 2006 – November 4, 2006 | 1 |
| Floyd Mayweather, Jr. | November 4, 2006 – June 6, 2008 (vacated) | 1 |
| Andre Berto def. Miguel Ángel Rodríguez |
June 21, 2008 – April 16, 2011 | 5 |
| Victor Ortiz | April 16, 2011 – September 17, 2011 | 0 |
| Floyd Mayweather, Jr. | September 17, 2011 – Present |
Read more about this topic: List Of WBC World Champions