Cruiserweight
| Name | Reign period | No. of successful defenses |
| Marvin Camel | March 31, 1980 – November 25, 1980 | 0 |
| Carlos De León | November 25, 1980 – June 27, 1982 | 1 |
| S. T. Gordon | June 27, 1982 – July 17, 1983 | 1 |
| Carlos De León | July 17, 1983 – June 6, 1985 | 3 |
| Alfonso Ratliff | June 6, 1985 – September 21, 1985 | 0 |
| Bernard Benton | September 21, 1985 – March 22, 1986 | 0 |
| Carlos De León | March 22, 1986 – April 9, 1988 | 3 |
| Evander Holyfield | April 9, 1988 – April 9, 1989 (vacated) | 0 |
| Carlos De León def. Sammy Reeson |
May 17, 1989 – July 27, 1990 | 3 |
| Massimiliano Duran | July 27, 1990 – July 20, 1991 | 1 |
| Anaclet Wamba | July 20, 1991 – December 30, 1994 | 7 |
| Marcelo Domínguez | July 25, 1995 – February 21, 1998 | 5 |
| Juan Carlos Gómez | February 21, 1998 – February 19, 2002 (vacated) | 10 |
| Wayne Braithwaite def. Vincenzo Cantatore |
October 11, 2002 – April 2, 2005 | 3 |
| Jean-Marc Mormeck | April 2, 2005 – January 7, 2006 | 0 |
| O'Neil Bell | January 7, 2006 – March 17, 2007 | 0 |
| Jean-Marc Mormeck | March 17, 2007 – November 10, 2007 | 0 |
| David Haye | November 10, 2007 – May 12, 2008 (vacated) | 1 |
| Giacobbe Fragomeni def. Rudolf Kraj |
October 24, 2008 – November 21, 2009 | 1 |
| Zsolt Erdei | November 21, 2009 – January 13, 2010 (vacated) | 0 |
| Krzysztof Włodarczyk def. Giacobbe Fragomeni |
May 15, 2010 – Present | 4 |
Read more about this topic: List Of WBC World Champions