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- Dan Dare: Pilot of the Future (Commodore 64, Amstrad CPC, ZX Spectrum)
- Danger Girl (PlayStation)
- Daredevil (GBA)
- The Darkness (PlayStation 3, Xbox 360)
- DC Universe:
- Mortal Kombat vs. DC Universe (PlayStation 3, Xbox 360)
- DC Universe Online (PlayStation 3, PC)
- Injustice: Gods Among Us (PlayStation 3, Xbox 360, Wii U)
- Deadpool (PlayStation 3, Xbox 360)
- Dennis the Menace (SNES, Game Boy)
- Dick Tracy (NES, Mega Drive)
- Dinosaurs For Hire (Genesis)
- Duckman (PC)
Read more about this topic: List Of Video Games Based On Comics