S
| Satellite 7 | Sega | Sega | |
| Scramble Spirits | Sega | Sega | |
| Secret Commando | - | - | |
| Senha | - | - | |
| Sepentes | - | - | |
| Shadow Dancer | Sega | Sega | |
| Shinobi | Sega | Sega | |
| Slap Shot | Sanritsu | Sega | |
| Snowball | Flying Edge | ||
| Sonic Drift 2 | Sega | Sega | |
| Sonic the Hedgehog | Sega | Sega | |
| Special Criminal Investigation | Taito Corporation | Sega | |
| Sodoku | - | - | |
| Super Space Invaders | Taito Corporation | Domark | |
| Super Tennis (Great Tennis in Japan) | Sega | Sega |
Read more about this topic: List Of Tec Toy Master System 131 Games