D
- Olivia d'Abo
- Gabriel Damon
- Timothy Dang
- Henry Darrow
- Bud Davis
- Daniel Davis
- John de Lancie
- Jonathan Del Arco
- Salvador Delgado (Latin American dub: voice of Data)
- Chris Demetral
- John DeMita
- Victoria Dillard
- Nick Dimitri
- Susan Diol
- Lawrence Dobkin
- Juliana Donald
- James Doohan
- Michael Dorn
- Charles Douglass
- Ellen Albertini Dow
- J. Downing
- Marta DuBois
- Kirsten Dunst
- John Durbin
- Eugene Dynarski
Read more about this topic: List Of Star Trek: The Next Generation Cast Members