D
- Danny K (Danny Koppel), R&B singer-songwriter
- Dan Tshanda (Daniel Ndivhiseni Tshanda
- Dalom Kids
- Dave Matthews, Rock singer-songwriter
- AB de Villiers, cricketer and singer
- Steven DeGroote (1953–1989), classical pianist and winner of the Van Cliburn International Piano Competition
- Fanie de Jager, operatic tenor
- Die Antwoord
- Dingus, classic ska band
- Bonginkosi Dlamini, poet, actor, and singer also known as Zola
- Dollar Brand
- Dorp
- Downfall
- Dragon Invasion, Reptilian death metal
- Jabulani Dubazana, singer, Ladysmith Black Mambazo
- Lucky Dube
- Duck and Cover, hard rock band
- Ampie du Preez, singer and guitarist
- Johnny Dyani (1945–1986), jazz double bassist
Read more about this topic: List Of South African Musicians