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- O.L.L Secondary Technical School
- Oasis Christian Academy
- Obefos International School
- Obiri Yeboah Secondary
- Obo Presbyterian Junior Secondary
- Obuasi Secondary Technical School
- Oda Attafuah Secondary Technical
- Oda Secondary School
- Odoben Secondary
- Odorgonno Secondary School
- Odorkor 1 Junior Secondary School
- Ofoase Primary School
- Ofoase Secondary Technical School
- Ofori Panyin Secondary School
- Oforikrom M/A Primary & Junior High School, Oforikrom - Kumasi
- Oguaa Senior Secondary Technical
- Okomeso L/A Primary
- Okomfo Anokye Secondary
- Okomfo Anokye Secondary School
- Okuapemman Senior High School
- OLA Senior Secondary School
- Oniwaa Memorial Junior Secondary School
- Onwi D/A Junior Secondary
- Open Heavens Preparatory School
- Opinaman L/A Junior Secondary
- Opoku Ware Girls Vocational
- Opoku Ware Junior Secondary School
- Opoku Ware School
- Oppon Memorial Secondary
- O'Reilly Secondary
- Osei Asibey Sekyere International School
- Osei Kyeretwie Secondary School
- Osei Tutu International
- Osino Secondary School
- Osu Home Junior Secondary, in Osu
- Osu Presby '2' J.S.S
- Osu Presby Secondary
- Osudoku Senior Secondary Technical School
- Otinibi M/A J.H.S
- Oti Secondary Technical
- Otuam International School, in Ekumfi Otuam
- Otuam Methodist Primary School, in Ekumfi Otuam
- Otuam Methodist J.S.S
- Otuo Acheampong International
- Our Lady of Providence Secondary
- Our Lady International/Junior Secondary School
- Our Lady of Mercy Secondary
- Owerrimman Secondary Technical School
- The Owl's Nest International School
- Open Hearted Academy, in Kasoa
- Oxford International Preparatory & J.S.S, in Konongo
- Oyoko Methodist Senior High School
Read more about this topic: List Of Schools In Ghana