Me
- Meade River - Alaska
- Meadow River - West Virginia
- Meadow Valley Wash - Nevada
- Mecan River - Wisconsin
- Mechums River - Virginia
- Medicine Bow River - Colorado, Wyoming
- Medicine Lodge River - Kansas, Oklahoma
- Medina River - Texas
- Meduxnekeag River - Maine
- Meeme River - Wisconsin
- Meherrin River - Virginia, North Carolina
- Melozitna River - Alaska
- Melvin River - New Hampshire
- Mendenhall River - Alaska
- Menominee River - Michigan, Wisconsin
- Menominee River - Wisconsin, Illinois
- Menomonee River - Wisconsin
- Meramec River - Missouri
- Merced River - California
- Merrimack River - Massachusetts, New Hampshire
- Merrymeeting River - New Hampshire
- Meshik River - Alaska
- Metedeconk River - New Jersey
- Methow River - Washington
- Metolius River - Oregon
- Mettawee River - Vermont, New York
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