List of Numbered Highways in South Carolina - Interstate Highways

Interstate Highways

Interstate highways that pass through the state of South Carolina, along with auxiliary routes:

• Interstate 20, spans nearly the entire state from west to east, passing through Florence, Columbia and Aiken.
  • Business Spur 20, a business spur extension into Florence.
  • Interstate 520, a partial beltway in N. Augusta.
• Interstate 26, travels from northwest to southeast through Spartanburg, Columbia and Charleston area.
  • Interstate 126, a spur into Columbia from the northwest.
  • Interstate 526, a partial beltway of Charleston, running from U.S. Route 17 west of the city north to I-26 and back east and south to US 17 east of Charleston.
  • Business Spur 526, a business spur extension into Mt. Pleasant ending at SC 703.
• Interstate 77, travels mostly north/south through central South Carolina from Columbia to Rock Hill.
• Interstate 85, travels northeast/southwest through the state, linking Anderson, Greenville, Spartanburg and Gaffney.
  • Business Loop 85, a business freeway loop in Spartanburg.
  • Interstate 185, a spur into Greenville as a partial toll road ending at I-385 southeast of Greenville.
  • Interstate 385, a spur into Greenville from the southeast to Interstate 26 towards Columbia.
  • Business Spur 385, a business spur into Greenville from the northwest.
  • Interstate 585, a spur route in Spartanburg from the northwest.
  • Business Spur 585, a business spur in Spartanburg from the northwest.
• Interstate 95, traverses the state's Coastal Plain region through Dillon, Florence, Walterboro, Ridgeland and Hardeeville.