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- Jonathan Sacks - Rabbi.
- Ross Samson - Professional rugby player with London Irish and Scotland U20 and 7s cap. Studied History.
- William Scammell - Poet.
- Sean Scully - painter.
- Mark Sephton - Professor of Organic Geochemistry and Meteoritics, Imperial College London.
- Nigel Shadbolt - Computer Scientist.
- Tom Shakespeare - Geneticist.
- Jo Shapcott - Poet.
- James Shapiro - Canadian surgeon and scientist.
- Jack Shepherd - Actor and playwright.
- Mark Shucksmith - Professor.
- Chris Simms - Crime thriller novel author.
- Iain Smith - Scottish politician.
- Paul Smith - Singer, Maxïmo Park.
- Paul Smith - Politician, former member of Bristol city council.
- John Snow - Father of modern epidemiology through discovery of cholera transmission through water and a leader in the adoption of anaesthesia.
- Ed Stafford - Explorer, walking the length of the Amazon River.
- Chris Steele-Perkins - Photographer.
- Chris Stevenson - Academic.
- Di Stewart - Sky Sports News Reader.
- Miodrag Stojković - Genetics Researcher.
- Miriam Stoppard - Physician, author and agony aunt.
- Peter Straughan - Playwright and short-story writer.
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Jonathan Sacks
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Nigel Shadbolt
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Paul Smith
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Iain Smith
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Ed Stafford
Read more about this topic: List Of Newcastle University People