- Titina De Filippo (1898–1965)
- Liana Del Balzo (1899–1982) (born in Buenos Aires, Argentina)
- Carla Del Poggio (born 1925)
- Orchidea De Santis (born 1948)
- Giuliana De Sio (born 1957)
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- Irasema Dilián (1924–1996) (Polish actress born in Rio de Janeiro, Brazil)
- Silvia Dionisio (born 1951)
- Miria Di San Servolo (1923–1991)
- Ada Dondini (1883–1958)
- Eleonora Duse (1858–1924)
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