C
- Cam'ron (Untertainment/Epic)
- Cash Out (Bases Loaded/Epic)
- Camp 22
- Cappadonna (Razor Sharp/Epic)
- Cartel
- Cha Cha
- Keshia Chanté
- Tina Charles
- Charley D. and Milo
- Charlie Daniels Band (Epic Nashville)
- Bill Chase
- Cheap Trick
- Cher Lloyd (The X Factor UK contestant)
- Chevelle
- CeCe Frey
- Bill Chinnock
- Christie
- Ciara
- Gigliola Cinquetti
- John Cooper Clarke
- Stanley Clarke
- The Clash
- Cleopatra
- George Clinton (550 Music/Epic)
- Creed (outside US)
- Cobra
- Tammy Cochran (Epic Nashville)
- Compton's Most Wanted
- Sarah Connor
- Brad Cotter (Epic Nashville)
- The Cover Girls
- Beverley Craven
- Cry Before Dawn
- Bobbie Cryner (Epic Nashville)
- Culture Beat (550 Music/Epic)
- Culture Club (US)
- Cycle Sluts from Hell
- Chris Rene (The X Factor USA, season 1, contestant)
Read more about this topic: List Of Epic Records Artists