D
- D.A.C. (1922–1923)
- Dagmar (1922–1927)
- Dale (1974)
- Daniels (1916–1924)
- Dan Patch (1910–1911)
- Darby (1909–1910)
- Darling (1901–1902)
- Darling (1917)
- Darrin (1946, 1955–1958)
- Dart (1910)
- Dart (1914)
- Davenport (1902)
- Davis (1908–1929)
- Davis (1914)
- Davis (1947–1949)
- Davis Steam Car (1921)
- Davis Totem (1921–1922)
- Dawson (1904)
- Dawson Auto-Mobile (1899-1901)
- Day (1911–1914)
- Dayton (1914)
- Dayton Electric (1911–1915)
- Deal (1905–1911)
- Decatur (1910–1911)
- Decatur (1914–1915)
- Decker (1902–1903)
- Deere-Clark (1906; Deere 1907)
- Deering Magnetic (1918–1919)
- De La Vergne (1895–1896)
- Delling (1924–1927)
- Delmore (1921–1923)
- De Luxe (1906–1908)
- De Mars Electric (1905–1906; Blakeslee Electric 1906; Williams Electric 1906-1907; Byrider Electric 1907-1910)
- DeMot or DeMotCar (1910–1911)
- De Motte (1904)
- Denneed (1916)
- Derain (1908–1911)
- Desberon (1901–1904)
- De Schaum (1908–1909)
- De Shaw (1907–1909)
- Des Moines (1902)
- De Soto (1913–1914)
- DeSoto (1928–1961)
- De Tamble (1908–1913)
- Detroit (1904–1908)
- Detroit (1904)
- Detroit Cyclecar (1913–1914)
- Detroit-Dearborn (1910–1911)
- Detroit Electric (1907–1939)
- Detroiter (1912–1917)
- Detroit-Oxford (1905–1906) (see also Oxford)
- Detroit-Speedster (1913–1914; Saginaw Speedster 1914)
- Detroit Steam (1922) (see also Trask-Detroit)
- De Vaux (1931–1932)
- De Vaux Continental (1932–1934)
- DeWitt (1909–1910)
- Dewabout (1900–1901)
- Dey Electric (1917–1919)
- Dey Griswold (1895–1898)
- Diamond (1914–1915)
- Diamond T (1905–1911)
- Diana (1925–1928)
- Dile (1914–1917)
- Dingfelder (1903)
- Disbrow (1917–1918)
- Dispatch (1910)
- Dixie (1908–1910)
- Dixie (1916)
- Dixie Flyer (1916–1923)
- D.L.G. (1907)
- Doble (1914–1918, 1922–1931)
- Dodge (1914–1915)
- Dodgeson (1926)
- Dodo (1912)
- Dolson (1904–1907)
- Dorris (1906–1926)
- Dort (1915–1924)
- Douglas (1918–1919)
- Dovell (circa 1980s)
- Downing (1914–1915)
- Downing-Detroit (1913–1915)
- Dragon (1906–1908)
- Dragon (1920–1921)
- Drake (1921–1922)
- Drexel (1916–1917)
- Driggs-Seabury (1915; Driggs 1921-1923)
- Drummond (1916–1917)
- Dual-Ghia (1956–1958)
- Duck (Jackson model)
- Dudly Bug (1913–1915)
- Dudgeon Steam (1857, 1866)
- Duer (1907–1910)
- Duesenberg (1913–1937)
- Dumont (see Santos Dumont)
- Dunn (1916–1918)
- Duplex (1908–1909)
- Du Pont (1919–1931)
- Duquesne (1904–1906)
- Duquesne (1912–1913)
- Durant (1921–1931)
- Durocar (1906–1911)
- Duryea (1893–1917)
- Dyke (or St Louis) (1899–1901; Dyke-Britton 1904)
- Dymaxion (1933)
Read more about this topic: List Of Defunct Automobile Manufacturers Of The United States