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- Roscoe Dash (Zone 4/Geffen/Interscope)
- Dashboard Confessional
- Ester Dean (Zone 4/Interscope)
- Lana Del Rey (Interscope/Stranger)
- Esmée Denters (Tennman/Interscope)
- Destinee & Paris
- Diddy (Bad Boy/Interscope)
- The Diplomats
- Disco Curtis (MySpace/Interscope)
- Dr. Dre (Aftermath/Interscope)
Read more about this topic: List Of Current Interscope Records Artists