MC
- mC – (s) Millicoulomb
- MC
- (s) Macau (FIPS 10-4 territory code)
- (i) Master of Ceremonies
- (s) Megacoulomb
- (i) Military Cross (bravery award)
- (s) Monaco (ISO 3166 digram)
- (i) Mortar Carrier
- (s) Eleven Hundred (in Roman numerals)
- MCA
- (i) Master of Computer Applications
- Micro Channel Architecture
- MultiChannel Analyzer
- Music Corporation of America, the original name of the now-defunct MCA Inc.
- MCC
- (i) Marylebone Cricket Club
- Mission Control Center
- Motor Control Center
- Movement Control Centre
- MCD
- (i) Minimal Cerebral Dysfunction
- Minor civil division (U.S. Census term)
- MCDL – (i) Model Composition Definition Language
- MCFT – (i) Modified Compression Field Theory
- MCG – (i) Melbourne Cricket Ground
- MC&G – (i) Mapping, Charting, and Geodesy
- MCI – (i) Microwave Communications, Inc.
- MCIS – (i) Mellon Collie and the Infinite Sadness
- MCM – (i) Mine Counter-Measures
- MCMV – (i) Mine Counter-Measure Vessel
- MCNC
- (i) Microelectronics Center of North Carolina
- (i) Mixing Condensation Nucleus Counter
- MCO
- (i) Major Combat Operation
- (s) Monaco (ISO 3166 trigram)
- (i) Movement Control Officer
- MCP
- (i) Maintenance Collection Point
- Male Chauvinist Pig
- MCR – (i) My Chemical Romance
- MCSF – (i) Marine Corps Security Forces
- MCT – (i) Movement Control Team
- MCTIS – (i) Mounted Co-operative Target Identification System
- MCU
- (i) Marine Corps University
- Marvel Cinematic Universe
- Medium close-up (camera direction in British TV scripts)
- (p) Microcontroller unit
- (i) Milk clotting units
- Ming Chuan University
- Minimum coded unit (digital imaging)
- Multipoint control unit
- Municipal Credit Union (New York)
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