Lead time bias is the bias that occurs when two tests for a disease are compared, and one test (the new, experimental one) diagnoses the disease earlier, but there is no effect on the outcome of the disease—it may appear that the test prolonged survival, when in fact it only resulted in earlier diagnosis when compared to traditional methods. It is an important factor when evaluating the effectiveness of a specific test.
Read more about Lead Time Bias: Relationship Between Screening and Survival
Famous quotes containing the words lead, time and/or bias:
“A point has been reached where the peoples of the Americas must take cognizance of growing ill-will, of marked trends toward aggression, of increasing armaments, of shortening tempers—a situation which has in it many of the elements that lead to the tragedy of general war.... Peace is threatened by those who seek selfish power.”
—Franklin D. Roosevelt (1882–1945)
“There has been in our time a lack of reliance on language and a lack of experimentation which are frightening to anyone who sees them as symptoms. We know the phenomenon of stage-fright: it holds the player shivering, incapable of speech or action. Perhaps there is an audience-fright which the play can feel, which leaves him with these incapacities.”
—Muriel Rukeyser (1913–1980)
“The solar system has no anxiety about its reputation, and the credit of truth and honesty is as safe; nor have I any fear that a skeptical bias can be given by leaning hard on the sides of fate, of practical power, or of trade, which the doctrine of Faith cannot down-weigh.”
—Ralph Waldo Emerson (1803–1882)