Kusu or KUSU may refer to:
- "tortoise" in Chinese.
- "fart" in Tamil, a South Indian language spoken in Tamil Nadu
- "awamori" - aged awamori, a drink native to Okinawa, Japan
- Kusu, Mie, a former town in Mie Prefecture, Japan
- Kusu, Ōita, a town in Ōita Prefecture, Japan
- Kusu District, Ōita, a district in Ōita Prefecture, Japan
- Kusu Station, a railway station in Japan
- Kusu Island, an island in Singapore
- KUSU-FM, a radio station in Logan, Utah, the United States
- Keele University Students' Union, a university students' union at Keele University, the United Kingdom