Professional Boxing Record
| 33 Wins (24 knockouts), 4 loss(s), 1 Draw, 0 No Contest | |||||||
| Res. | Record | Opponnent | Type | Rd., Time | Date | Location | Notes |
| Loss | 33-4-1 | Manuel Pérez | SD | 10 | 2012-07-21 | Oasis Hotel Complex, Cancún, Quintana Roo | |
| Win | 33-3-1 | Eric Cruz | UD | 10 | 2012-04-21 | Coliseo Roger L. Mendoza, Caguas | |
| Loss | 32-3-1 | Paulie Malignaggi | UD | 10 | 2011-04-09 | MGM Grand Garden Arena, Las Vegas, Nevada | |
| Win | 32-2-1 | Christopher Henry | TKO | 4 (10), 1:19 | 2010-11-05 | Coliseo Cosme Beitia Salamo, Cataño | |
| Loss | 31-2-1 | Saúl Álvarez | TKO | 9 (10), 2:51 | 2010-05-01 | MGM Grand Garden Arena, Las Vegas, Nevada | |
| Win | 31-1-1 | Ilido Julio | TKO | 6 (8) | 2009-12-19 | Coliseo Roger L. Mendoza, Caguas | |
| Win | 30-1-1 | Martin Ramirez | KO | 3 (8), 2:52 | 2009-09-26 | Coliseo Héctor Solá Bezares, Caguas | |
| Win | 29-1-1 | Anthony Woods | TKO | 4 (8), 2:24 | 2009-08-29 | Coliseo Ruben Viera, Las Piedras | |
| Draw | 28-1-1 | Prawet Singwancha | MD | 12 | 2007-05-11 | Coliseo Angel 'Cholo' Espada, Salinas | |
| Win | 28-1-0 | Ivan Hernandez | TKO | 10 (10), 1:57 | 2006-08-04 | Coliseo Pedrín Zorrilla, Hato Rey | |
| Loss | 27-1-0 | Juan Díaz | UD | 12 | 2006-04-08 | Thomas & Mack Center, Las Vegas, Nevada | For WBA World Lightweight title. |
| Win | 26-0-0 | Ubaldo Hernandez | KO | 7 (10), 2:59 | 2006-01-20 | Activity Center, Maywood, California | |
| Win | 25-0-0 | Genaro Trazancos | TKO | 7 (12), 1:00 | 2005-03-04 | Coliseo Pedrín Zorrilla, Hato Rey | Won vacant WBO Inter-Continental Super Featherweight title. |
| Win | 24-0-0 | Armando Cordoba | KO | 1 (12), 1:27 | 2005-01-29 | Coliseo Ruben Rodriguez, Hato Rey | Won vacant WBO NABO Lightweight title. |
| Win | 23-0-0 | Alfred Kotey | UD | 10 | 2004-08-06 | Coliseo Pedrín Zorrilla, Hato Rey | |
| Win | 22-0-0 | Luis Alfonso Lizarraga | KO | 1 (11), 2:27 | 2004-05-14 | Dodge Theater, Phoenix, Arizona | Won IBC Intercontinental Lightweight title. |
Read more about this topic: Jose Cotto
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