John Farley is the name of:
- John H. Farley (1846–1922), Mayor of Cleveland, Ohio
- John Murphy Farley (1842–1918), Irish-American cardinal, seventh bishop (fourth archbishop) of the Roman Catholic diocese of New York
- John P. Farley (born 1968), American actor and comedian
- John Wells Farley (1878–1959), American football player and coach, head football coach at the University of Maine and Harvard University
- John Farley (MP) for Gloucester (UK Parliament constituency)