HOXB1

Identifiers Symbols HOXB1; HCFP3; HOX2; HOX2I; Hox-2.9 External IDs OMIM: 142968 MGI: 96182 HomoloGene: 1615 GeneCards: HOXB1 Gene

Gene Ontology
Molecular function	• DNA binding • sequence-specific DNA binding transcription factor activity • protein domain specific binding • sequence-specific DNA binding
Cellular component	• nucleus • nucleolus • cytoplasm
Biological process	• transcription, DNA-dependent • regulation of transcription, DNA-dependent • multicellular organismal development • pattern specification process • anterior/posterior pattern specification • rhombomere 4 development • rhombomere 5 development • facial nerve structural organization • facial nucleus development • positive regulation of transcription from RNA polymerase II promoter • embryonic skeletal system morphogenesis
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 3211 15407 Ensembl ENSG00000120094 ENSMUSG00000018973 UniProt P14653 P17919 RefSeq (mRNA) NM_002144 NM_008266 RefSeq (protein) NP_002135 NP_032292 Location (UCSC) Chr 17:
46.61 – 46.61 Mb Chr 11:
96.37 – 96.37 Mb PubMed search

Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene.

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.