C
- C. Thomas Howell (born 1966), American actor
- Carla Howell (born 1955), American Libertarian politician
- Cedric Howell (1896–1919), Australian fighter pilot
- Charles Howell (1905–1974), British Labour politician and member of Parliament
- Charles Howell III (born 1979), American golfer
- Charles Andrew Howell III (born 1930), American businessman
- Charles Augustus Howell (1840–1890), British-Portuguese art dealer
- Charles Henry Howell (c. 1824–1905), British architect
- Charles R. Howell (1904–1973), American politician and member of the House of Representatives
- Charmaine Howell (born 1975), Jamaican athlete
- Christopher Howell (born c. 1946), American poet
- Christopher Howell (cricketer) (born 1977), English cricketer
- Clarence Howell (1881–1936), American chess master
- Clark Howell (1863–1936), American newspaper man and politician
- Clement Howell (1935–1987), Turks and Caicos politician
- Colin Howell (born 1959), Northern Irish murderer
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