Homology directed repair (HDR) is a mechanism in cells to repair double strand DNA lesions. This repair mechanism can only be used by the cell when there is a homologue piece of DNA present in the nucleus, mostly in G2 and S phase of the cell cycle. When the homologue DNA piece is absent, another process called non-homologous end joining (NHEJ) can take place instead.
Read more about Homology Directed Repair: Cancer Suppression, Biological Pathway, Reference and Further Reading
Famous quotes containing the words directed and/or repair:
“What is clear is that Christianity directed increased attention to childhood. For the first time in history it seemed important to decide what the moral status of children was. In the midst of this sometimes excessive concern, a new sympathy for children was promoted. Sometimes this meant criticizing adults. . . . So far as parents were put on the defensive in this way, the beginning of the Christian era marks a revolution in the child’s status.”
—C. John Sommerville (20th century)
“The United Nations cannot do anything, and never could; it is not an animate entity or agent. It is a place, a stage, a forum and a shrine ... a place to which powerful people can repair when they are fearful about the course on which their own rhetoric seems to be propelling them.”
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