HK2

HK2

Identifiers Symbols HK2; HKII; HXK2 External IDs OMIM: 601125 MGI: 1315197 HomoloGene: 37273 ChEMBL: 2640 GeneCards: HK2 Gene EC number 2.7.1.1

Gene Ontology
Molecular function	• glucokinase activity • hexokinase activity • ATP binding • glucose binding • fructokinase activity • mannokinase activity
Cellular component	• mitochondrial outer membrane • cytosol
Biological process	• cellular glucose homeostasis • carbohydrate metabolic process • glycolysis • lactation • apoptotic mitochondrial changes • hexose transport • glucose transport • small molecule metabolic process • regulation of glucose import • glucose 6-phosphate metabolic process • transmembrane transport
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 3099 15277 Ensembl ENSG00000159399 ENSMUSG00000000628 UniProt P52789 O08528 RefSeq (mRNA) NM_000189 NM_013820 RefSeq (protein) NP_000180 NP_038848 Location (UCSC) Chr 2:
75.06 – 75.12 Mb Chr 6:
82.73 – 82.77 Mb PubMed search

Hexokinase 2 also known as HK2 is an enzyme which in humans is encoded by the HK2 gene.