Classification, and Relationships To Other Conditions
There are competing systems for classifying histiocytoses. According to the 1999 classification proposed by the World Health Organization, they can be divided into three categories. However, the classifications in ICD10 and MeSH are slightly different, as shown below:
Name | WHO | ICD10 | MeSH |
Langerhans cell histiocytosis (LCH) | I | D76.0 | Langerhans-cell histiocytosis |
Juvenile xanthogranuloma (JXG) | II | D76.3 | non-Langerhans-cell histiocytosis |
Hemophagocytic lymphohistiocytosis (HLH) | II | D76.1 | non-Langerhans-cell histiocytosis |
Niemann–Pick disease | II | E75.2 | non-Langerhans-cell histiocytosis |
Sea-blue histiocytosis | II | - | non-Langerhans-cell histiocytosis |
Acute monocytic leukemia | III | C93.0 | malignant histiocytic disorders |
Malignant histiocytosis | III | C96.1 | malignant histiocytic disorders |
Erdheim–Chester disease | II | C96.1 | malignant histiocytic disorders |
Types of LCH have also been known as "Eosinophilic Granuloma", "Hand-Schuller-Christian Disease", "Letterer-Siwe Disease", and "Histiocytosis X". (See Langerhans cell histiocytosis for details).
Alternatively, histiocytoses may be divided into the following groups:
-
- X-type histiocytoses
- Non-X histiocytoses
Read more about this topic: Histiocytosis
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