Hfq Binding S RNA

Hfq Binding S RNA

A Hfq binding sRNA is an sRNA that binds the bacterial RNA binding protein called Hfq. A number of bacterial small RNAs which have been shown to bind to Hfq have been characterised (see list). Many of these RNAs share a similar structure composed of three stem-loops. Recent studies have expanded this list and experimentally validated a total of 64 Hfq binding sRNA in Salmonella Typhimurium. Genomic SELEX has been used to show that Hfq binding RNAs are enriched in the sequence motif 5'-AAYAAYAA-3'.