Other
- In December 1968, Emory University coed Barbara Jane Mackle, became one of the history of the FBI's most notorius kidnapping cases. At the height of a particularly severe influenza outbreak she was apparently abducted from a De Kalb County motel, taken to, and buried alive inside a box in a shallow trench with directions on where to find her sent to the FBI. The accused, Gary Steven Krist, an apparent full-time professional smuggler of humans from Latin America attempting to gain funds for further trafficking. The box was buried in a densely wooded area just inside of the county's northwestern boundaries.
- On March 6, 1978, both Hustler magazine publisher Larry Flynt and his local lawyer, Gene Reeves, Jr., were shot by a gunman in Lawrenceville, after walking back from a cafeteria near to a courthouse while on trial.
- In 1997 (June 12–15), the county became one of less than half-a-dozen U.S. locations in Bilderberg history to ever host a Bilderberg Conference meeting, at the former (demolished) Renaissance Pine Isle Resort & Golf Club at Lake Lanier, in Buford.
- Late CNN reporter John Holliman (October 23, 1948–September 12, 1998) was a resident of and died in a car crash in Snellville.
- In Feb. 2001, Mohamed Atta and Marwan al-Shehhi, terrorists in the 9/11 attacks, stayed in Norcross, Georgia, and trained at an airport used by the Gwinnett County Sheriffs Department, in Lawrenceville.
- On April 26, 2005, Jennifer Wilbanks, known as the Runaway Bride "disappeared" in Duluth and led authorities on a cross country search and investigation.
- Natina Reed, 32, of Atlanta-based R&B group Blaque was killed near Norcross on October 26, 2012, after being struck by a car while attempting to cross a five-lane highway on foot towards a near-by convienence store.
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