GSK3B

Identifiers Symbol GSK3B External IDs OMIM: 605004 MGI: 1861437 HomoloGene: 55629 ChEMBL: 262 GeneCards: GSK3B Gene EC number 2.7.11.26 2.7.11.1, 2.7.11.26

Gene Ontology
Molecular function RNA polymerase II transcription factor binding
p53 binding
protein serine/threonine kinase activity
integrin binding
protein binding
ATP binding
beta-catenin binding
kinase activity
protein kinase binding
ubiquitin protein ligase binding
protein kinase A catalytic subunit binding
ionotropic glutamate receptor binding
tau protein binding
tau-protein kinase activity
NF-kappaB binding
Cellular component nucleus
nucleolus
cytoplasm
centrosome
cytosol
plasma membrane
growth cone
ribonucleoprotein complex
beta-catenin destruction complex
neuronal cell body
dendritic spine
dendritic shaft
membrane raft
Biological process re-entry into mitotic cell cycle
epithelial to mesenchymal transition
positive regulation of cell-matrix adhesion
glycogen metabolic process
regulation of gene expression by genetic imprinting
protein phosphorylation
protein export from nucleus
ER overload response
epidermal growth factor receptor signaling pathway
axon guidance
myoblast fusion
fibroblast growth factor receptor signaling pathway
organ morphogenesis
response to lithium ion
positive regulation of peptidyl-threonine phosphorylation
cell migration
peptidyl-serine phosphorylation
hippocampus development
establishment of cell polarity
negative regulation of protein complex assembly
positive regulation of protein complex assembly
negative regulation of protein binding
positive regulation of protein binding
positive regulation of Rac GTPase activity
regulation of microtubule-based process
positive regulation of peptidyl-serine phosphorylation
protein localization to microtubule
intracellular signal transduction
response to drug
negative regulation of apoptotic process
negative regulation of MAP kinase activity
hypermethylation of CpG island
canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process
fat cell differentiation
negative regulation of glycogen biosynthetic process
positive regulation of protein catabolic process
negative regulation of transcription, DNA-dependent
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein export from nucleus
nerve growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
regulation of neuronal synaptic plasticity
negative regulation of dendrite morphogenesis
negative regulation of NFAT protein import into nucleus
canonical Wnt receptor signaling pathway
superior temporal gyrus development
negative regulation of canonical Wnt receptor signaling pathway
negative regulation of type B pancreatic cell development
negative regulation of glycogen (starch) synthase activity
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2932 56637 Ensembl ENSG00000082701 ENSMUSG00000022812 UniProt P49841 Q9WV60 RefSeq (mRNA) NM_001146156 NM_019827 RefSeq (protein) NP_001139628 NP_062801 Location (UCSC) Chr 3:
119.54 – 119.81 Mb Chr 16:
38.09 – 38.25 Mb PubMed search

Glycogen synthase kinase 3 beta, also known as GSK3B, is an enzyme that in humans is encoded by the GSK3B gene.

Read more about GSK3B:  Function, Interactions