Gold Standard Ambiguity
Sometimes "Gold Standard test" refers to the best performing test available. In these cases, there is no other criterion against which it can be compared and it is equivalent to a definition. When referring to this meaning, gold standard tests are normally not performed at all. This is because the "gold standard" test may be difficult to perform or may be impossible to perform on a living person (i.e. the test is performed as part of an autopsy or may take too long for the results of the test to be available to be clinically useful).
Other times, "Gold standard" does not refer to the best performing test available, but the best available under reasonable conditions. For example, in this sense, a MRI is the gold standard for brain tumour diagnosis, though it is not as good as a biopsy. In this case the sensitivity and specifity of the gold standard are not 100% and it is said to be an "imperfect gold standard" or "Alloyed gold standard"
Read more about this topic: Gold Standard (test)
Famous quotes containing the words gold, standard and/or ambiguity:
“When you have eaten your fill and have built fine houses and live in them, and when your herds and flocks have multiplied, and your silver and gold is multiplied, and all that you have is multiplied, then do not exalt yourself, forgetting the LORD your God, who brought you out of the land of Egypt, out of the house of slavery...”
—Bible: Hebrew, Deuteronomy 8:12-14.
“I don’t have any problem with a reporter or a news person who says the President is uninformed on this issue or that issue. I don’t think any of us would challenge that. I do have a problem with the singular focus on this, as if that’s the only standard by which we ought to judge a president. What we learned in the last administration was how little having an encyclopedic grasp of all the facts has to do with governing.”
—David R. Gergen (b. 1942)
“Indeed, it is that ambiguity and ambivalence which often is so puzzling in women—the quality of shifting from child to woman, the seeming helplessness one moment and the utter self-reliance the next that baffle us, that seem most difficult to understand. These are the qualities that make her a mystery, the qualities that provoked Freud to complain, “What does a woman want?””
—Lillian Breslow Rubin (20th century)