Glucagon Receptor Family

The glucagon receptor family is a group of closely related G-protein coupled receptors which include:

  • Glucagon receptor
  • Glucagon-like peptide 1 receptor
  • Glucagon-like peptide 2 receptor
  • Gastric inhibitory polypeptide receptor

The first three receptors bind closely related peptide hormones (glucagon, glucagon-like peptide-1, glucagon-like peptide-2) derived from the proglucagon polypeptide. The last receptor binds gastric inhibitory polypeptide.

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