GENESIS (software) - Applications

Applications

Most current applications for GENESIS involve realistic simulations of biological systems.It is usually used to simulate the behavior of larger brain structures (ex: Cerebral Cortex) These studies most often occur in lab courses in neural simulation at CalTech and the Marine Biological Laboratory at Woods Hole, Massachusetts

GENESIS can be used in combination with Yale University’s software called NEURON as a means for scientists to collaborate to construct a physical description of the nervous system. The GENESIS software can also be used with Kinetikit in the modeling of signal transduction pathways.

GENESIS has been used in many studies, a list of which can be found at the following site:

  • GENESIS Publications

Some of these studies involve research that focuses on the development of software that would be useful across many disciplines. Others are studies of neurons, such as purkinje cells. These studies used GENESIS to simulate Purkinje cells and could be useful for the planning and development of later experiments using the GENESIS software.

Other applications worth mentioning are the biomedical applications of the software. For example: Can the GENESIS software be transformed into software that could be encoded on an implanted device that could simulate the nervous system in individuals with neurodegenerative diseases? The following video focuses on an implanted GENESIS device developed by St. Judes in Europe and suggests that it can.

  • Video: GENESIS Implanted Device

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