Businesses, Services, Protocols
- "G.D.S.", a song on the 2004 Saku album by Japanese rock band Dir en grey
- Gaelic Digital Service, an initiative which includes BBC Radio nan Gàidheal in Scotland
- Game Developers Session, annual conference
- Global Dialing Scheme, a numbering plan for video and voice over IP networks
- Global Directory Server, a directory for user information and other applications data
- Global distribution system or computer reservations system, a system for searching, reserving, and purchasing travel products
- Google Desktop Search, a software application for searching files stored on a local area network or a hard disk
- UK Government Decontamination Service, a UK Government executive agency dealing with chemical, biological, radiological, and nuclear resistance and recovery
- Government Digital Service, part of the Cabinet Office
- Graph Dynamical Systems, a field of applied mathematics concerned with evolving networks
- GDSII (Graphic Data System II), a format for integrated circuit layout data
- Gribskovbanens Driftsselskab, a Danish railway company
- Global Display Solutions, a company based in Italy, USA, Romania and China that manufacturers specialty industrial LCD displays
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