GATA3
| Gene Ontology | |
|---|---|
| Molecular function | • transcription regulatory region sequence-specific DNA binding • RNA polymerase II core promoter sequence-specific DNA binding • core promoter proximal region sequence-specific DNA binding • core promoter sequence-specific DNA binding • nucleic acid binding transcription factor activity • RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription • RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription • enhancer sequence-specific DNA binding • DNA binding • sequence-specific DNA binding transcription factor activity • transcription coactivator activity • interleukin-2 receptor binding • protein binding • transcription factor binding • zinc ion binding • transcription regulatory region DNA binding • metal ion binding • protein dimerization activity • E-box binding • HMG box domain binding |
| Cellular component | • nuclear chromatin • nucleus • nucleoplasm • nucleolus |
| Biological process | • in utero embryonic development • cell fate determination • neuron migration • type IV hypersensitivity • kidney development • mesonephros development • lens development in camera-type eye • pro-T cell differentiation • aortic valve morphogenesis • cardiac right ventricle morphogenesis • ventricular septum development • transcription from RNA polymerase II promoter • defense response • humoral immune response • signal transduction • axon guidance • blood coagulation • negative regulation of cell proliferation • male gonad development • response to virus • anatomical structure morphogenesis • post-embryonic development • positive regulation of signal transduction • response to gamma radiation • positive regulation of endothelial cell migration • phosphatidylinositol 3-kinase cascade • erythrocyte differentiation • TOR signaling cascade • negative regulation of interferon-gamma production • negative regulation of interleukin-2 production • positive regulation of interleukin-13 production • positive regulation of interleukin-4 production • positive regulation of interleukin-5 production • negative regulation of mammary gland epithelial cell proliferation • embryonic hemopoiesis • cellular response to interferon-alpha • ureter maturation • parathyroid hormone secretion • regulation of cytokine biosynthetic process • norepinephrine biosynthetic process • inner ear morphogenesis • response to drug • regulation of CD4-positive, alpha-beta T cell differentiation • regulation of neuron apoptotic process • ear development • response to estrogen stimulus • thymic T cell selection • T-helper 2 cell differentiation • response to ethanol • positive regulation of T cell differentiation • negative regulation of fat cell differentiation • negative regulation of cell cycle • negative regulation of transcription, DNA-dependent • positive regulation of transcription, DNA-dependent • positive regulation of transcription from RNA polymerase II promoter • cell maturation • sympathetic nervous system development • thymus development • developmental growth • anatomical structure formation involved in morphogenesis • negative regulation of inflammatory response • T cell receptor signaling pathway • regulation of histone H3-K4 methylation • positive regulation of protein kinase B signaling cascade • parathyroid gland development • pharyngeal system development • uterus development • mesenchymal to epithelial transition • mast cell differentiation • ureteric bud formation • regulation of histone H3-K27 methylation • canonical Wnt receptor signaling pathway involved in metanephric kidney development • cellular response to interleukin-4 • cellular response to tumor necrosis factor • otic vesicle development • cellular response to BMP stimulus • positive regulation of ureteric bud formation • nephric duct morphogenesis • nephric duct formation • regulation of nephron tubule epithelial cell differentiation • interleukin-4 secretion • interferon-gamma secretion • lymphocyte migration • regulation of establishment of cell polarity • negative regulation of cell motility • negative regulation of endothelial cell apoptotic process • negative regulation of cell proliferation involved in mesonephros development • positive regulation of thyroid hormone generation • positive regulation of interleukin-5 secretion • positive regulation of interleukin-13 secretion • positive regulation of transcription regulatory region DNA binding • regulation of cellular response to X-ray • negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation • negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation |
| Sources: Amigo / QuickGO | |
8.1 – 8.12 Mb
9.86 – 9.89 Mb
Trans-acting T-cell-specific transcription factor GATA-3 is a protein that in humans is encoded by the GATA3 gene.
Read more about GATA3: Function, Clinical Significance, Interactions