Computers and Software
- AMD Fusion, a next-generation microprocessor design
- ColdFusion, a rapid application development platform
- Compiz Fusion, a community maintained set of plugins for the Compiz Window Manager
- Exterro Fusion, a software company based in Portland, Oregon
- Eyeon Fusion, a visual effects package
- Fusion Systems, an IT consulting firm based in Tokyo, Hong Kong and Shanghai
- IBRIX Fusion, a highly scalable parallel file system
- Kega Fusion, a Sega multi-console emulator
- Loop fusion, a compiler program-optimization transformation that replaces replacing multiple loops with a single one
- NetObjects Fusion, a web design program
- Oracle Fusion Middleware, a portfolio of standards-based software products that spans multiple services
- Sensor fusion, the combining of sensory data or data derived from sensory data from disparate sources
- VMware Fusion, virtual machine software product by VMware, Inc.
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