Frontotemporal Lobar Degeneration
Frontotemporal lobar degeneration (FTLD) is the name for a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain, with sparing of the parietal and occipital lobes.
In the over 65 age group, FTLD is probably the fourth most common cause of dementia after Alzheimer's disease, dementia with Lewy bodies and vascular dementia. In the below 65 age group, it is the second most common cause after Alzheimer's disease. In some patients the symptoms of FTLD and Alzheimer's may overlap
FTLD is the pathological term for the clinical syndrome Frontotemporal dementia, which can be subdivided as follows:
- behavioural-variant frontotemporal dementia (bvFTLD)
- semantic dementia (SD)
- progressive nonfluent aphasia (PNS)
Read more about Frontotemporal Lobar Degeneration: Histology, Genetics, Imaging, Examples
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