FOXD3

FOXD3

Identifiers Symbols FOXD3; AIS1; Genesis; HFH2; VAMAS2 External IDs OMIM: 611539 MGI: 1347473 HomoloGene: 49239 GeneCards: FOXD3 Gene

Gene Ontology
Molecular function	• RNA polymerase II regulatory region sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription • double-stranded DNA binding • sequence-specific DNA binding transcription factor activity • RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity • protein binding • transcription factor binding • DNA binding, bending
Cellular component	• nuclear chromatin • transcription factor complex
Biological process	• negative regulation of transcription from RNA polymerase II promoter • branching involved in ureteric bud morphogenesis • in utero embryonic development • neural crest cell migration • kidney development • trophectodermal cell differentiation • embryonic placenta development • pattern specification process • peripheral nervous system development • melanocyte differentiation • positive regulation of transcription from RNA polymerase II promoter • enteric nervous system development • sympathetic nervous system development • axon extension involved in axon guidance • lateral line nerve glial cell development • iridophore differentiation • regulation of sequence-specific DNA binding transcription factor activity • cartilage development
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 27022 15221 Ensembl ENSG00000187140 ENSMUSG00000067261 UniProt Q9UJU5 Q61060 RefSeq (mRNA) NM_012183 NM_010425 RefSeq (protein) NP_036315 NP_034555 Location (UCSC) Chr 1:
63.79 – 63.79 Mb Chr 4:
99.66 – 99.66 Mb PubMed search

Forkhead box D3 also known as FOXD3 is a forkhead protein that in humans is encoded by the FOXD3 gene.