Founder Mutation - Serial Founder Effect

Serial Founder Effect

Serial founder effects have occurred when populations migrate over long distances. Such long distance migrations typically involve relatively rapid movements followed by periods of settlement. The populations in each migration carry only a subset of the genetic diversity carried from previous migrations. As a result, genetic differentiation tends to increase with geographic distance as described by the "Isolation by distance" model. The migration of humans out of Africa is characterized by serial founder effects. Africa has the highest degree of genetic diversity, which is consistent with an African origin of modern humans. After the initial migration from Africa, the Indian subcontinent was the first major settling point for modern humans. Consequently, India has the second highest genetic diversity in the world. In general, the genetic diversity of the Indian continent is a subset of Africa, and the genetic diversity outside Africa is a subset of India.

Read more about this topic:  Founder Mutation

Famous quotes containing the words serial, founder and/or effect:

    The serial number of a human specimen is the face, that accidental and unrepeatable combination of features. It reflects neither character nor soul, nor what we call the self. The face is only the serial number of a specimen.
    Milan Kundera (b. 1929)

    The first man, who after enclosing a piece of ground, took it into his head to say, this is mine, and found people simple enough to believe him, was the real founder of civil society.
    Jean-Jacques Rousseau (1712–1778)

    I guess what I’ve really discovered is the humanizing effect of children in my life—stretching me, humbling me. Maybe my thighs aren’t as thin as they used to be. Maybe my getaways aren’t as glamorous. Still I like the woman that motherhood has helped me to become.
    Susan Lapinski (20th century)