Fly Base - Contents

Contents

FlyBase contains a complete annotation of the Drosophila melanogaster genome that is updated several times per year. It also includes a searchable bibliography of research on Drosophila genetics in the last century. Information on current researchers, and a partial pedigree of relationships between current researchers, is searchable, based on registration of the participating scientist. The site also provides a large database of images illustrating the full genome, and several movies detailing embryogenesis.

Search Strategies - Gene reports for genes from all twelve sequenced Drosophila genomes are available in FlyBase. There are four main ways this data can be browsed: Precomputed Files, BLAST, Gbrowse, and Gene Report Pages. Gbrowse and precomputed files are for genome wide analysis, bioinformatics, and comparative genomics. BLAST and gene report pages are for a specific gene, protein, or region across the species.

When looking for cytology there are two main tools available. Use Cytosearch when looking for cytologically-mapped genes or deficiencies, that haven’t been molecularly mapped to the sequence. Use Gbrowse when looking for molecularly mapped sequences, insertions, or Affymetrix probes.

There are two main query tools in FlyBase. The first main query tool is called Jump to Gene (J2G). This is found in the top right of the blue navigation bar on every page of FlyBase. This tool is useful when you know exactly what you are looking for and want to go to the report page with that data. The second main query tool is called QuickSearch. This is located on the FlyBase homepage. This tool is most useful when you want to look up something quickly that you may only know a little about. Searching can be performed within D. melanogaster only or within all species. Data other than genes can be searched using the ‘data class’ menu.

FlyBase has a very useful Site Map to help navigate through the content of the website.